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教授

近期通知

教授

首页师资队伍教授

王咸文

发布日期:

2021-08-10

浏览次数：

21439

姓　名：

王咸文

职　称：

东南学者特聘教授

职　务：

博士生导师

所属系：

生物医学材料系

邮　箱：

xianwenwang@ahmu.edu.cn

电　话：

个人学习工作简介

个人简介

王咸文，博士，安徽医科大学东南学者，教授（三类人才），博士生导师，东南博士后合作导师。中国生物物理学会自由基生物学与自由基医学分会青年委员，Chinese Chemical Letters，Burns & Trauma及Military Medical Research杂志青年编委，入选2023年Nanoscale（IF: 8.307）2023年 Emerging Investigators（新锐科学家）。迄今为止共发表SCI论文40多余篇，其中申请人以一作或通讯作者发表SCI论文30余篇，包括Chemical Society Reviews（2篇）、Journal of the American Chemical Society（1篇），Nano Today（3篇）、Bioactive Materials（1篇）、Materials Horizons（1篇），Coordination Chemistry Reviews（2篇），Applied Physics Reviews（1篇），Military Medical Research（1篇），Chemistry of Materials（1篇）、Small（1篇），Acta Biomaterialia（2篇），Nano Research（2篇）和ACS Applied Materials & Interfaces（2篇）等，其中IF大于10分以上的论文20篇，IF大于20分以上的论文6篇。论文总次数超过2900余次，ESI高被引论文9篇，H-index：30。申请人的研究成果先后受到X-MOL和Materials Views等众多媒体和网站的亮点报道，多篇文章被选为封面论文。此外，王咸文博士现为ACS Nano，Nano Micro Letters，Acta Biomaterialia，Materials Today Bio、ACS Applied Materials & Interfaces等40多个SCI期刊的特邀审稿人。

课题组主页：https://www.x-mol.com/groups/xianwenwang

学习与工作简历：

2021.8-至今安徽医科大学生物医学工程学院东南学者特聘教授，博士生导师

2018.9-2021.6苏州大学材料科学与工程专业（导师：李述汤院士，刘庄教授，程亮教授）

2015.9-2018.6合肥工业大学制药工程专业（导师：查正宝教授）

2011.9-2015.6安徽师范大学化学工程与工艺专业（导师：魏先文教授，吴孔林副教授）

学术任职：

1. 中国生物物理学会自由基生物学与自由基医学分会青年委员

2. Chinese Chemical Letters 、Burns & Trauma及Military Medical Research杂志青年编委

3. Molecules（IF：4.927），Frontiers in Chemistry（IF：5.545）和Pharmaceuticals （IF：5.215）的客座编辑（Guest Editor）

4. ACS Nano，Nano Micro Letters，Acta Biomaterialia，Materials Today Bio、ACS Applied Materials & Interfaces等40多个SCI期刊的特邀审稿人

主要研究领域与方向

硕士研究生招生专业：药学，药理学

博士研究生招生专业: 药学，药理学

研究方向：

1. 纳米材料在肿瘤治疗方面的应用，主要包括声动力治疗，光热治疗，化学动力治疗等;

2. 纳米材料的在抗菌方面的应用;

3. 抗炎纳米制剂的开发及其抗炎机制研究；

4. 新型止血材料、组织再生（创面愈合）材料的设计与开发；

5. 新型纳米材料在神经类疾病中的应用及探索。

代表性研究成果

1. 发展了钛基纳米材料用于增强的声动力治疗；

2. 发展了系列纳米酶用于肿瘤的诊断和治疗；

3. 制备了纳米酶用于高效的抗菌及伤口修复。

目前承担科研项目

1. 安徽医科大学东南学者启动基金（1406012201），2021年-至今，主持，在研

2. 2022年国家自然科学基金青年项目（5220020455），2023年-至今，主持，在研

3. 2022年安徽省自然科学基金-青年项目（2208085QC81），2022年-至今，主持，在研

4. 2021年安徽医科大学基础与临床合作研究提升计划（2021xkjT028），2022年-至今，主持，在研

5. 2021年度抗炎免疫药物教育部重点实验室开放课题（KFJJ-2021-11），2022年-至今，主持，在研

6. 2022年海南省生物医学工程重点实验室开放课题（Opening Foundation 2022004）， 2022年-至今，主持，在研

获奖情况

1. 入选2023年Nanoscale（IF: 8.307）2023 Emerging Investigators（新锐科学家）

2. 2021年苏州大学优秀毕业生；苏州大学研究生学术标兵

3. 2020年博士国家奖学金；朱敬文奖学金

4. 2018年合肥工业大学研究生年度人物

5. 2017年硕士国家奖学金；合肥工业大学研究生十佳科技标兵

6. 2015年安徽省创新之星

7. 2015年安徽师范大学第四届本科科研论文大赛一等奖

著作论文（代表作）

1. Xianwen Wang, Xiaoyan Zhong, Lixin Bai, Jun Xu, Fei Gong, Ziliang Dong, Zhijuan Yang, Zhijie Zeng, Zhuang Liu, Liang Cheng*. Ultrafine titanium monoxide (TiO_1+x) nanorods for enhanced sonodynamic therapy. Journal of the American Chemical Society, 2020, 142, 6527-6537. (中科院一区 IF: 16.383, TOP 期刊，ESI高被引论文)

2. Xianwen Wang, Xiaoyan Zhong, Jianxiang Li, Zhuang Liu*, and Liang Cheng*. Inorganic nanomaterials with rapid clearance for biomedical applications. Chemical Society Reviews, 2021, 50, 8669-8742. (中科院一区 IF: 60.615，TOP 期刊)

3. Subin Son^#, Ji Hyeon Kim^#, Xianwen Wang^#, Chuangli Zhang^#, Shin A Yoon^#, Jinwoo Shin, Amit Sharma, Min Hee Lee, Liang Cheng and Jiasheng Wu. Multifunctional sonosensitizers in sonodynamic cancer therapy. Chemical Society Reviews, 2020, 49, 3244-3261. (中科院一区 IF: 60.615，TOP 期刊)

4. Konglin Wu^#, Dongdong Zhu^#, Xingliang Dai^#, Wanni Wang, Xiaoyan Zhong, Zhaobin Fang, Cheng Peng, Xianwen Wei, Haisheng Qian, Xulin Chen, Xianwen Wang*, Zhengbao Zha*, and Liang Cheng*. Bimetallic oxide Cu_1.5Mn_1.5O₄ cage-like frame nanospheres with triple enzyme-like activities for bacterial-infected wound therapy. Nano Today, 2022, 43, 101380. (中科院一区 IF: 18.962，TOP 期刊)

5. Xianwen Wang, Xiyu Wang, Qingfen Yue, Huizhong Xu, Xiaoyan Zhong, Lina Sun, Guangqiang Li, Yuehan Gong, Nailing Yang, Zhanhui Wang*, Zhuang Liu, Liang Cheng*. Liquid exfoliation of TiN nanodots as novel sonosensitizers for photothermal-enhanced sonodynamic therapy against cancer. Nano Today, 2021, 39, 101170. (中科院一区 IF: 18.962，TOP 期刊)

6. Xianwen Wang, Xianyan Zhong, Zhuang Liu, Liang Cheng*. Recent progress of chemodynamic therapy-induced combination cancer therapy. Nano Today, 2020, 35, 100946. (中科院一区 IF: 18.962，TOP 期刊)

7. Xianwen Wang^#, Qianqian Shi^#, Zhengbao Zha*, Dongdong Zhu, Lirong Zheng, Luoxiang Shi, Xianwen Wei, Lian Lian, Konglin Wu*, Liang Cheng*. Copper single-atom catalysts with photothermal performance and enhanced nanozyme activity for bacteria‐infected wound therapy. Bioactive Materials, 2021, 6, 4389-4401. (中科院一区 IF: 16.874，TOP 期刊)

8. Xianwen Wang, Xiaoyan Zhong, Liang Cheng*. Titanium-based nanomaterials for cancer theranostics. Coordination Chemistry Reviews, 2021, 430, 213662. (中科院一区 IF: 24.833，TOP 期刊)

9. Xianwen Wang, Liang Cheng*. Multifunctional Prussian blue-based nanomaterials: Preparation, modification, and theranostic applications. Coordination Chemistry Reviews, 2020, 419, 213393. (中科院一区 IF: 24.833，TOP 期刊)

10. Xianwen Wang, Xiyu Wang, Xiaoyan Zhong, Guangqiang Li, Zhijuan Yang, Yuehan Gong, Zhuang Liu*, Liang Cheng*. V-TiO₂ nanospindles with regulating tumor microenvironment performance for enhanced sonodynamic cancer therapy. Applied Physics Reviews, 2020, 7, 041411. (中科院一区 IF: 19.527，TOP 期刊，Featured Article)

11. Xianwen Wang, Xiaoyan Zhong, Fei Gong, Yu Chao, Liang Cheng*. Newly developed strategies for improving sonodynamic therapy. Materials Horizons, 2020, 7, 2028-2046. (中科院一区 IF: 15.717，TOP 期刊，Back cover)

12. Qinglong Guo^#, Xingliang Dai^#, Mengyuan Yin, Hongwei Cheng*, Haisheng Qian, Hua Wang, Daoming Zhu*, and Xianwen Wang*. Nanosensitizers for Sonodynamic Therapy of Glioblastoma: Current Progress and Future Perspectives. Military Medical Research, 2022, 9, 1-18. (中科院一区 IF: 34.915，TOP 期刊)

13. Yan Ma^#, Kai Jiang^#, Hongrang Chen^#, Qianqian Shi, Hang Liu, Xiaoyan Zhong, Haisheng Qian, Xulin Chen, Liang Cheng*, Xianwen Wang*. Liquid Exfoliation of V₈C₇ Nanodots as Peroxidase-Like Nanozymes for Photothermal-Catalytic Synergistic Antibacterial Treatment. Acta Biomaterialia, 2022, 149, 359-372. (中科院一区 IF: 10.633，TOP 期刊)

14. Shipeng Ning^#, Xingliang Dai^#, Weiwei Tang^#, Qinglong Guo, Meng Lyu, Daoming Zhu, Wei Zhang, Haisheng Qian*, Xiaxi Yao*, Xianwen Wang*. Cancer Cell Membrane-Coated C-TiO₂ Hollow Nanoshells for Combined Sonodynamic and Hypoxia-Activated Chemotherapy. Acta Biomaterialia, 2022, DOI: org/10.1016/j.actbio.2022.08.067. (中科院一区 IF: 10.633，TOP 期刊)

15. Xianwen Wang, Xiaoyan Zhong, Huali Lei, Yuehao Geng, Qi Zhao*, Fei Gong, Zhijuan Yang, Ziliang Dong, Zhuang Liu, Liang Cheng*. Hollow Cu₂Se nanozymes for tumor photothermal-catalytic therapy. Chemistry of Materials, 2019, 31, 6174-6186. (中科院一区 IF: 10.508，TOP 期刊)

16. Daoming Zhu^#, Ruoyu Ling^#, Hao Chen^#, Meng Lyu, Haisheng Qian, Konglin Wu*, Guoxin Li*, and Xianwen Wang*. Biomimetic copper single-atom nanozyme system for self-enhanced nanocatalytic tumor therapy. Nano Research, 2022, 15, 7320-7328. (中科院一区 IF: 10.269，TOP 期刊)

17. Weihong Guo^#, Tao Wang^#, Chunyu Huang^#, Shipeng Ning^#, Qinglong Guo, Wei Zhang, Huawei Yang, Daoming Zhu, Qinqin Huang*, Haisheng Qian, Xianwen Wang*. Platelet Membrane-Coated C-TiO₂ Hollow Nanospheres for Combined Sonodynamic and Alkyl-Radical Cancer Therapy. Nano Research, 2022, DOI: org/10.1007/s12274-022-4646-2. (中科院一区 IF: 10.269，TOP 期刊)

18. Xingliang Dai, Yuxuan Shao, Xuefeng Tian, Xiaoyan Cao, Lei Ye, Peng Gao*, Hongwei Cheng*, and Xianwen Wang*. Fusion between Glioma Stem Cells and Mesenchymal Stem Cells Promotes Malignant Progression in 3D-Bioprinted Models. ACS Applied Materials & Interfaces, 2022, 14, 35344–35356. (中科院一区 IF: 10.383，TOP 期刊)

19. Xianwen Wang^#, Fei Li^#, Xu Yan^#, Yan Ma*, Zhao-Hua Miao, Liang Dong, Huajian Chen, Yang Lu*, Zhengbao Zha*. Ambient aqueous synthesis of ultrasmall Ni_{0. 85}Se nanoparticles for noninvasive photoacoustic imaging and combined photothermal-chemotherapy of cancer. ACS Applied Materials & Interfaces, 2017, 9, 41782-41793. (中科院一区 IF: 10.383，TOP 期刊)

20. Zhan Zhou^#, Xianwen Wang^#, Hui Zhang, Haoxin Huang, Lina Sun, Lu Ma, Yonghua Du, Chengjie Pei, Qinghua Zhang, Hai Li, Lufang Ma, Lin Gu, Zhuang Liu, Liang Cheng*, Chaoliang Tan*. Activating layered metal oxide nanomaterials via structural engineering as biodegradable nanoagents for photothermal cancer therapy. Small, 2021, 17, 2007486. (中科院一区 IF: 15.153，TOP 期刊)

21. Wei Zhang^#, Xingliang Dai^#, Xu Jin, Muchen Huang, Jie Shan, Xulin Chen, Haisheng Qian, Zenghong Chen*, Xianwen Wang*. Promotion of wound healing by a thermosensitive and sprayable hydrogel with nanozyme activity and anti-inflammatory properties. Smart Materials in Medicine, 2023, 4, 134-145. (国产TOP 期刊)

22. Xiaoyan Zhong^#, Xingliang Dai^#, Yan Wang, Hua Wang, Haisheng Qian, and Xianwen Wang*. Copper-Based Nanomaterials for Cancer Theranostics. Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology, 2022, e1797. (中科院二区 IF: 9.423，TOP 期刊)

23. Dongdong Liu^#, Xingliang Dai^#, Lei Ye, Hua Wang, Haisheng Qian*, Hongwei Cheng*, and Xianwen Wang*. Nanotechnology Meets Glioblastoma Multiforme: Emerging Therapeutic Strategies.Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology, 2022, e1838. (中科院二区 IF: 9.423，TOP 期刊)

24. Fan Cao^#, Si-Yu Gui^#, Xiang Gao^#, Wei Zhang, Zi-Yue Fu, Li-Ming Tao*, Zheng-Xuan Jiang*, Xulin Chen, Haisheng Qian, Xianwen Wang*. Research Progress of Natural Product-based Nanomaterials for the Treatment of Inflammation-Related Diseases. Materials & Design, 2022, 110686. (中科院一区 IF: 9.417，TOP 期刊)

25. Xianwen Wang, Xiaoyan Zhong, Zhengbao Zha*, Gang He, Zhaohua Miao, Huali Lei, Qunyi Luo, Rui Zhang, Zhuang Liu, Liang Cheng*. Biodegradable CoS₂ nanoclusters for photothermal-enhanced chemodynamic therapy. Applied Materials Today, 2020, 18, 100464. (中科院一区 IF: 8.663，TOP 期刊)

26. Yuqi Yang, Xianwen Wang*, Haisheng Qian, Liang Cheng*. Titanium-based sonosensitizers for sonodynamic cancer therapy. Applied Materials Today, 2021, 25, 101215. (中科院一区 IF: 8.663，TOP 期刊)

27. Mengyuan Yin^#, Xiangcun Chen^#, Qinglong Guo^#, Liang Xiao, Peng Gao, Dandan Zang, Jun Dong, Zhengbao Zha, Xingliang Dai*, and Xianwen Wang*. Ultrasmall zirconium carbide nanodots for synergistic photothermal-radiotherapy of glioma. Nanoscale, 2022, DOI: org/10.1039/D2NR04239H. (中科院一区 IF: 8.307，TOP 期刊)

28. Xianwen Wang, Liang Cheng. Multifunctional two-dimensional nanocomposites for photothermal-based combined cancer therapy. Nanoscale, 2019, 11, 15685-15708. (中科院一区 IF: 8.307，TOP 期刊, 背封面论文)

29. Xianwen Wang^#, Zhaohua Miao^#, Yan Ma, Huajian Chen, Haisheng Qian*, Zhengbao Zha*. One-pot solution synthesis of shape-controlled copper selenide nanostructures and their potential applications in photocatalysis and photothermal therapy. Nanoscale, 2017, 9, 14512-14519. (中科院一区 IF: 8.307，TOP 期刊, 背封面论文)

30. Gang He^#, Yan Ma^#, Hu Zhou^#, Siyuan Sun, Xianwen Wang*, Haisheng Qian, Yan Xu, Zhaohua Miao*, Zhengbao Zha*. Mesoporous NiS₂ nanospheres as a hydrophobic anticancer drug delivery vehicle for synergistic photothermal–chemotherapy. Journal of Materials Chemistry B, 2019, 7, 143-149. (中科院二区 IF: 7.571)

31. Yanbin Sun^#, Xianwen Wang^#, Linxin Fan, Xianli Xie, Zhaohua Miao, Yan Ma, Tao He*, Zhengbao Zha*. Facile synthesis of monodisperse chromogenic amylose–iodine nanoparticles as an efficient broad-spectrum antibacterial agent. Journal of Materials Chemistry B, 2020, 8, 3010-3015. (中科院二区 IF: 7.571)

32. Xianwen Wang, Linxin Fan, Liang Cheng*, Yanbin Sun, Xiyu Wang, Xiaoyan Zhong, Qianqian Shi, Fei Gong, Yu Yang, Yan Ma, Zhaohua Miao, Zhengbao Zha*. Biodegradable nickel disulfide nanozymes with GSH-depleting function for high-efficiency photothermal-catalytic antibacterial therapy. iScience, 2020, 23, 101281. (Cell子刊 中科院二区 IF: 6.107，综合性期刊)

33. Xianwen Wang, Yan Ma, Huajian Chen, Xiaoyi Wu, Haisheng Qian, Xianzhu Yang, Zhengbao Zha. Novel doxorubicin loaded PEGylated cuprous telluride nanocrystals for combined photothermal-chemo cancer treatment. Colloids and Surfaces B: Biointerfaces, 2017, 152, 449-458. (中科院二区 IF: 5.999，TOP 期刊)

34. Yan Ma^#, Xianwen Wang^#, Huajian Chen, Zhaohua Miao, Gang He, Junhong Zhou, Zhengbao Zha. Polyacrylic acid functionalized Co_0.85Se nanoparticles: an ultrasmall pH-responsive nanocarrier for synergistic photothermal-chemo treatment of cancer. ACS Biomaterials Science & Engineering, 2018, 4, 547-557. (中科院二区 IF: 5.395)

35. Xianwen Wang, Konglin Wu*, Kun Liu, Weizhi Wang, Yaoxiang Yue, Mengli Zhao, Juan Cheng, Jiang Ming, Xianwen Wei*, Xiaowang Liu. Sacrificial template synthesis of (Co_xNi_1-x) _0.85Se nanostructures with different morphologies for reduction of 4-nitrophenol. CrystEngComm, 2015, 17, 734-739. (中科院二区 IF: 3.756)

36. Xianwen Wang*, Xiaoyan Zhong, Haisheng Qian, Zhengbao Zha*, in Nanozymes, CRC Press, 2021, pp. 199-224. (邀请章节)

#共同第一作者， *通讯作者

其他情况

课题组主页：https://www.x-mol.com/groups/xianwenwang

ResearchGate: https://www.researchgate.net/profile/Xianwen-Wang-3

ORCID iD: https://orcid.org/0000-0002-6343-440X

1. 尊重每一个学生，认真培养好每一个学生，做一个好的教育工作者，是我毕生的追求！

2. 欢迎勤奋好学，踏实肯干的本科生，硕士生，博士生，博士后加入本课题组！只要你愿意付出努力，成果不是问题，我愿意给予你最大的支持和帮助！

3. 欢迎联合培养的硕士及博士，欢迎各种形式的交流或者合作！联系邮箱：xianwenwang@ahmu.edu.cn。

更新日期（2021年10月）